Estradiol
Estrogen therapy for menopause symptoms
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Not available yet. Join the waitlist and we will email you when it launches in your state.
- U.S.-licensed providers and pharmacies
- 100% online, private consultation
- Prescription only if a provider decides it is right for you
- Tablet, patch, gel or vaginal cream
- For hot flashes, night sweats and dryness
- Only prescribed if a provider agrees it suits you
- Licensed U.S. providers
- Licensed U.S. pharmacies
- Price shown before you pay
- Pay for treatment only if prescribed
- Replies within one business day
- Online since 2002
What is estradiol therapy?
Estradiol is the main form of estrogen your body makes before menopause. When levels fall, many women get hot flashes, night sweats, broken sleep and vaginal dryness. Replacing some of that estrogen is the most effective treatment for hot flashes and night sweats.
Patches, gels and tablets treat symptoms throughout the body. A low-dose vaginal cream works mainly where it is applied, for dryness and discomfort. Women who still have a uterus also take progesterone to protect its lining.
Who it may be prescribed for
- Women with moderate to severe hot flashes or night sweats
- Women with vaginal dryness or discomfort during sex
- Healthy women under 60, or within ten years of their last period
How it works
Get your treatment in three simple steps
01Answer a few health questions
Tell us about your health, medicines and goals in an online questionnaire that takes about ten minutes.
02A licensed provider reviews it
A U.S.-licensed provider in your state reviews your answers, usually within about 24 hours, and messages you if they need more.
03Your treatment ships to you
If treatment is right for you, a licensed pharmacy prepares it and ships it to your door with clear instructions.
Why choose us
Real people, real support
HealthBuyRx does not stop at a prescription. Every plan includes access to your provider and a customer care team that answers.
Message your provider
Questions about your dose or side effects? Message your provider from the patient portal and hear back from someone who knows your history.
Start your visit
Customer care that answers
Our U.S.-based team helps with orders, billing and delivery by email or phone, and replies within one business day.
Contact our team
Do I also need progesterone?
If you still have a uterus and use estrogen that acts throughout the body, yes: progesterone protects the uterine lining. Low-dose vaginal estrogen usually does not need it.
Which form should I choose?
Patches and gels avoid the liver and may carry a lower clot risk than tablets. Your provider will help you weigh the options.
When will estradiol be available?
Join the waitlist and we will email you when it launches in your state.
Important safety information
Estrogen therapy is not right for everyone. Estrogen taken without a progestogen raises the risk of cancer of the uterine lining in women who still have a uterus. Estrogen, with or without a progestogen, can raise the risk of blood clots, stroke and gallbladder disease, and long-term combined use is linked with a small increase in breast cancer risk. In a large study of women 65 and older, hormone therapy was linked with a higher risk of dementia.
Do not use estrogen if you have had breast or uterine cancer, blood clots, a stroke or heart attack, liver disease or unexplained vaginal bleeding, or if you are pregnant. Your provider reviews your personal and family history first and prescribes the lowest dose that helps.